منابع مشابه
Clinical aspects of polycystic disease of the kidneys.
Seventy-eight patients were treated for polycystic disease of the kidneys. An analysis of the interval between the onset of symptoms and end-stage renal failure made it possible to give and accurate prognosis in individual cases. Pregnancy and urinary infection did not appear to accelerate deterioration of renal function, but Rovsing' operation precipitated renal failure in some cases. Forty-tw...
متن کاملErythropoietin in polycystic kidneys.
Erythropoietin (EPO) formation in kidneys of 18 patients with autosomal dominant polycystic kidney disease (ADPKD) was investigated. In 12 patients on hemodialysis and in 6 patients with preterminal renal failure serum, EPO was 29 +/- 7 and 16 +/- 1.5 mU/ml and hemoglobin concentrations were 11.0 +/- 0.6 and 12.7 +/- 1.2 g/dl, respectively. Cyst fluid from a total of 357 renal cysts was obtaine...
متن کاملGene profiling of polycystic kidneys.
BACKGROUND While the genetic basis of autosomal dominant polycystic kidney disease (ADPKD) has been clearly established, the pathogenesis of renal failure in ADPKD remains elusive. Cyst formation originates from proliferating renal tubular epithelial cells that de-differentiate. Fluid secretion with cyst expansion and reactive changes in the extracellular matrix composition combined with increa...
متن کاملA Case of Polycystic Disease of the Kidneys *Rearranged by Editor.
D. G., Hindu, male, aged 40 years, medical practitioner by profession, was admitted into the Astanga Ayurved Hospital on 9th November, 1934, for the treatment of the following complaints :? Bilateral tumour in the lumbar regions, persistent hematuria, and debility. Previous history.?The patient said that he firSj; noticed a growth in the right lumbar region about four years back. A few months a...
متن کاملA possible zebrafish model of polycystic kidney disease: knockdown of wnt5a causes cysts in zebrafish kidneys.
Polycystic kidney disease (PKD) is one of the most common causes of end-stage kidney disease, a devastating disease for which there is no cure. The molecular mechanisms leading to cyst formation in PKD remain somewhat unclear, but many genes are thought to be involved. Wnt5a is a non-canonical glycoprotein that regulates a wide range of developmental processes. Wnt5a works through the planar ce...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1953
ISSN: 0032-5473
DOI: 10.1136/pgmj.29.338.621